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| Friday, September 28, 2012 |
| Berkeley Springs at Moorefield | 7:30 p.m. |
| Bishop Donahue at Hundred | 7:30 p.m. |
| Braxton County at Liberty (Harrison) | 7:30 p.m. |
| Bridgeport at Elkins | 7:30 p.m. |
| Brooke at Point Pleasant | 7:30 p.m. |
| Buckhannon-Upshur at Lewis County | 7:30 p.m. |
| Cameron at Paden City | 7:30 p.m. |
| Capital at Hurricane | 7:30 p.m. |
| Chapmanville at James Monroe | 7:30 p.m. |
| Clay-battelle at Valley (Wetzel) | 7:30 p.m. |
| Fairmont Senior at University | 7:30 p.m. |
| Fayetteville at Man | 7:30 p.m. |
| Frankfort at Mountain Ridge, MD | 7:00 p.m. |
| Gilmer County at Tygarts Valley | 7:30 p.m. |
| Hampshire at Keyser | 7:00 p.m. |
| Hedgesville at Martinsburg | 7:00 p.m. |
| Independence at Sherman | 7:30 p.m. |
| John Marshall at Wheeling Park | 7:00 p.m. |
| Liberty (Raleigh) at Webster County | 7:30 p.m. |
| Lincoln at Grafton | 7:30 p.m. |
| Logan at Winfield | 7:30 p.m. |
| Magnolia at Monroe Central, OH | 7:00 p.m. |
| Mingo Central at Wayne | 7:30 p.m. |
| Montcalm at Midland Trail | 7:30 p.m. |
| Morgantown at Preston | 7:30 p.m. |
| Musselman at Jefferson | 7:00 p.m. |
| Nicholas County at Robert C. Byrd | 7:30 p.m. |
| North Marion at East Fairmont | 7:30 p.m. |
| Oak Glen at Weir | 7:00 p.m. |
| Parkersburg Catholic at Doddridge County | 7:30 p.m. |
| Pendleton County at East Hardy | 7:30 p.m. |
| Philip Barbour at Petersburg | 7:30 p.m. |
| Pikeview at Greenbrier West | 7:30 p.m. |
| Poca at Herbert Hoover | 7:30 p.m. |
| Ravenswood at Ritchie County | 7:30 p.m. |
| Richwood at Buffalo | 7:30 p.m. |
| River View at Wyoming East | 7:30 p.m. |
| Riverside at Parkersburg | 7:30 p.m. |
| Roane County at Ripley | 7:30 p.m. |
| Scott at Westside | 7:30 p.m. |
| Shady Spring at Oak Hill | 7:30 p.m. |
| Sissonville at Tolsia | 7:30 p.m. |
| South Charleston at St. Albans | 7:30 p.m. |
| South Harrison at Calhoun County | 7:30 p.m. |
| Spring Valley at Greenbrier East | 7:30 p.m. |
| St. Marys at Williamstown | 7:30 p.m. |
| Tug Valley at Hannan | 7:30 p.m. |
| Valley (Fayette) at Meadow Bridge | 7:30 p.m. |
| Van at Mount View | 7:30 p.m. |
| Woodrow Wilson at Cabell Midland | 7:30 p.m. |
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| Saturday, September 29, 2012 |
